AEMCA Practice Exam

What is the product of the reaction between angiotensin and ACE?

1. Angiotensin 1

2. Angiotensin 2

3. Aldosterone

4. Renin

The correct answer is: Angiotensin 2

The reaction between angiotensin and angiotensin-converting enzyme (ACE) produces angiotensin II, which is a potent vasoconstrictor and plays a crucial role in increasing blood pressure. Angiotensin I, which is the precursor, is formed from angiotensinogen through the action of renin. ACE then converts angiotensin I, which itself has limited biological activity, into angiotensin II by removing two amino acids. This conversion is significant in the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and fluid balance in the body. While substances like aldosterone and renin are involved in this hormonal regulation, they are not direct products of the interaction between angiotensin and ACE. Aldosterone is a product of adrenal cortex stimulation by angiotensin II, and renin is an enzyme that initiates the formation of angiotensin. Therefore, the correct answer highlights the direct product of the reaction between angiotensin and ACE as angiotensin II, distinguishing it from the other choices provided.