AEMCA Practice Exam

Which drugs are commonly used for opioid detoxification and maintenance?

1. Buprenorphine and naloxone

2. Hydromorphone and oxycodone

3. Methadone and levomethadyl acetate

4. Carfentanil and remifentanil

The correct answer is: Methadone and levomethadyl acetate

Buprenorphine and naloxone, along with methadone and levomethadyl acetate, are vital options for opioid detoxification and maintenance treatment. Methadone is a long-acting opioid used in controlled doses to reduce withdrawal symptoms and cravings, effectively stabilizing individuals undergoing detoxification from stronger opioids. Levomethadyl acetate also serves a similar purpose, though it's less commonly used. While buprenorphine is typically paired with naloxone to prevent misuse, it effectively alleviates withdrawal symptoms and cravings. The combination of these medications allows for a comprehensive approach to managing addiction, fostering a gradual tapering off of opioids for individuals seeking recovery. In contrast, hydromorphone and oxycodone are primarily used for pain management and do not have the specific characteristics required for detoxification and maintenance therapies. Furthermore, carfentanil and remifentanil are potent opioids intended for sedation and pain relief in specialized settings, not for detoxification or long-term maintenance. Therefore, the selection of methadone and levomethadyl acetate aligns with established practices for treating opioid use disorder, making it the correct answer.