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Which is a major sign of mumps?

  1. Fever and headache

  2. Swelling and pain in the parotid glands

  3. Red watery eyes

  4. Rash on the abdomen

The correct answer is: Swelling and pain in the parotid glands

The major sign of mumps is the swelling and pain in the parotid glands, which are the major salivary glands located near the jawline. This specific symptom, often referred to as parotitis, is a hallmark of the infection caused by the mumps virus. The inflammation can lead to noticeable swelling that may affect one or both sides of the face, often causing discomfort and difficulty in swallowing or opening the mouth. While fever and headache can be associated with mumps, they are common symptoms in various illnesses, not exclusive to mumps. Similarly, red watery eyes and a rash on the abdomen are not characteristic signs of mumps and might indicate other conditions altogether. The distinctiveness of parotid gland swelling makes it a key identifier of mumps, emphasizing the importance of recognizing this symptom in diagnosis and management of the disease.