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Which of the following is NOT a layer of the heart wall?

  1. Endocardium

  2. Epicardium

  3. Pericardium

  4. Myocardium

The correct answer is: Pericardium

The pericardium is indeed not a layer of the heart wall. Instead, it is a protective sac that surrounds the heart, consisting of two layers: the fibrous pericardium and the serous pericardium. The primary function of the pericardium is to provide a barrier that protects the heart from infections and to allow for the heart's movement within the thoracic cavity by reducing friction as the heart beats. On the other hand, the heart wall itself consists of three distinct layers: the endocardium, which lines the inner chambers of the heart; the myocardium, which is the muscular layer responsible for the heart's contractions; and the epicardium, which is the outer layer of the heart wall. Each of these layers plays a critical role in the function of the heart, contributing to its structure and operation in the circulatory system.